Yulvian Sani
| Abstract views: 1332 | PDF views: 744


Parasitic dermatitis may cause economic loss for livestock industry if it is not approriately controlled. Among the preventive measures available presently, the use of plant-derived insecticides is regarding as an alternative approach to control the disease since it is environmental and animal health safe. The purpose of this study was to assess the effects of mindi (Melia azedarach Linn.) extract leaves for controling Chrysomya bezziana in vitro and in vivo.The study showed that the methanolic extract of M.azedarach leaves affected various stages of C. bezziana larvae.A topical application of 0.25% methanol extract in vaseline mixture killed and inhibited the growth of larvae and reduced weight gain of both LI and LI larvae.The average mortality rate in a treated group (26%) was higher than a control group (19.2%).Greater reduction of average weight gain was also seen in the treated group (0.2719 gr.) compared to the control group (0.4761 gr). The larvae apparently had smaller size and wrinkled shape of anatomical structure seeming that they were inappropriately grown. While the average mortality rate of L2 was found higher in the treated group (46.8%) than the control group (22.4%). The leaf-methanol extract had greater effect to L2 than LI as seen higher mortality rate in L2 (46.8%) than the LI (26%). In conclusion that the higher dose rate of methanol extract applied will lead to high mortality of the larvae. The low mortality rate may be due to low concentration (0.25%) of leaf extract applied and short period of time for bioassay.These findings seem very promising, suggesting that may possible to increase larvicidal effects by increasing the concentration and time of assessment.


bioinsektisida, Melia azedarach, dermatitis, parasit, Chrysomya bezziana

Full Text:



Aminah NS, EJ Lestari dan Mardiana. 1989. Potensi ekstrak daun Melia azedarach Linn, (mindi) sebagai repelen. Makalah Biologi Kesehatan. Depertemen Kesehatan.

Borges LM, PH Ferri, WJ Silva, WC Silva and JG Silva. 2003. In vitro efficacy of extracts of Melia azedarach against the tick Boophilus microplus. Med. Vet. Emomol. 17 (2), 228 - 231.

Burkill 1H. 1966. A Dictionary of the Economic Product of the Malay Peninsula II, 1465. Ministry of Agriculture and Cooperative. Malaysia.

Bustami DA. 1995. Daya bunuh ekstrak air daun. buah dan kulit batang tumbuhan mindi (Melia azedarach Linn.) terhadap larva Aedes aegypti. Thesis Program Pasca Sarjana. Universitas Indonesia.

Dourmishey AL, LA Dourmishey and RA Schwartz. 2005. Pharmacology and therapeutic. Ivermectin: pharmacology and application in dermatology. Int. J. of Dermatology 44(12). 981.

Eisemann CH, LAY Johnston, M Broadmeadow, BM O'Sullivan, RA Donaldson, RD Pearson, T Voucolo and Kerr D. 1990. Acquired resistance of sheep to larvae of Lucilia cuprina, assessed in vivo and in vitro. Int. J. Parasitol. 20(3), 299-305.

Harborne JB. 1984. Phytochemical Methods: a Guide to Modern Techniques of Plant Analysis. 2"' edition. Chapman and Hall. London and New York.

Greenwood B. 1977. Haematology of the sheep and goat. IQ: Comparative Clinical Haematology, 305 - 344. RK Archer and Jeffcott (Eds.). Blackwell Scientific Publication. Oxford, London, Edinburgh and Melbourne.

Kirtikar KR, BD Basu and ICS An. 1980. Indian Medicinal Plants. 2nd Edition. Bishem Singh Mahendra Pal.Singh. India.

Nathan SS, G Savitha, UK George, A Narmadha, L Suganya and PG Chung. 2005. Efficacy of Melia azedarach L.. extract on the malarial vector Anopheles Stephens: Liston (Diptera: Culiucidae). Biosource Technol. 97(lssue 11). 1316 - 1323.

Schalm OW. 1965. Veterinary Haematology. 237 - 246 Lea and F'ebiger. Philadelphia. Sigit SH dan S Partoutomo. 1981. Myasis in Indonesia. Bull. Off. Int. Epizootics 19. 173-178.

Spradbery JP and JA VRiiniasiugham. 1980. Incidence of screwworm fly Chrysomya hezziana at the zoo Negara. Malaysia. Malays let. J. 7(1). 28 - 32.

Spradbery JP, RS Tozer, N Drevvett and 1VIJ Lindsey. 1985. The efficacy of ivermeclin against larvae of the screw-worm fly (Chrysomya bezziana). Aust. Vet. J. 62 (9). 311-4.

Spradbery JP, RS Tozcr and AA Pound. 1991. The efficacy of insecticides against screw-worm fly {Chrysomya bezziana). Aust. Vet. J. 68(10). 338 - 342.

Spradbery JP and J Kirk. 1992. Incidence of the old screwworm fly in the United Emirates of Arab. Vet. Record 127. 33.

Sukarsih, RS Tozer and MR Knox. 1989. Collection and case incidence of the old world screwworm fly, Chrysomya bezziana in three locations in Indonesia. Penyakit Hew an 21(38). 114-117.

Sukarsih, S Partoutumo, E Satria, G VVijffels, G Riding, C Eisemann and P Willadsen. 2000. Vaccination against the Old Screwworm fly (Chrysomya bezziana). Parasite Immunol. 22. 545-552.

Wandscheer CB, JE Duque, MA da Silva, Y Fukuyama, JL Wohlke. .1 Adclmann and JD Fontana. 2004. Larvacidal action of ethanolic extracts from fruit endocarps of Melia azedarach and Azedarachta tndica against the dengue mosquito Aedes aegypli. Toxicon 44(8), 829 - 835.

Watt JM and MG Breyer-Brandwijk. 1962. The Medicinal and Poisonous Plants in Southern Africa. E&S Livingstone. Edinburgh.


  • There are currently no refbacks.